中国科学院苏州纳米技术与纳米仿生研究所机构知识库
Advanced  
SINANO OpenIR  > 纳米生物医学与安全研究部  > 王强斌团队  > 期刊论文
题名: Coassembly of Tobacco Mosaic Virus Coat Proteins into Nanotubes with Uniform Length and Improved Physical Stability
作者: Zhou, K(周堃); Eiben, S; Wang, QB(王强斌)
通讯作者: Wang, QB(王强斌)
关键词: chimerical scaffold ;  coassembly ;  disulfide bond ;  length-controllability ;  physical stabilization ;  tobacco mosaic virus
刊名: ACS APPLIED MATERIALS & INTERFACES
发表日期: 2016
DOI: 10.1021/acsami.6b04321
卷: 8, 期:21, 页:13192-13196
收录类别: SCI
文章类型: 期刊论文
部门归属: 纳米生物医学与安全研究部
英文摘要: Using tobacco mosaic virus coat proteins (TMVcp) from both sources of the plant and bacterial expression systems as building blocks, we demonstrate here a coassembly strategy of TMV nanotubes in the presence of RNA. Specifically, plant-expressed cp (cp(p)) efficiently dominates the genomic RNA encapsidation to determine the length of assembled TMV nanotubes, whereas the incorporated Escherichia coli-expressed cp (cp(ec)) improves the physical stability of TMV nanotubes by introducing disulfide bonds between the interfaces of subunits. We expect this coassembly strategy can be expanded to other virus nanomaterials to obtain desired properties based on rationally designed protein-RNA and protein-protein interfacial interactions.
关键词[WOS]: NANOSTRUCTURES ; NANORODS ; RNA ; BIOTECHNOLOGY ; NANOPARTICLES ; NANOMATERIALS ; INTEGRATION ; PARTICLES ; PEPTIDES ; DISPLAY
语种: 英语
JCR小类分区: 一区
WOS记录号: WOS:000377150400003
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinano.ac.cn/handle/332007/4533
Appears in Collections:纳米生物医学与安全研究部_王强斌团队_期刊论文

Files in This Item:
File Name/ File Size Content Type Version Access License
Zhou-2016-Coassembly of Tobacco Mosaic Virus C.pdf(399KB)期刊论文作者接受稿限制开放View 联系获取全文

Recommended Citation:
Zhou, K,Eiben, S,Wang, QB. Coassembly of Tobacco Mosaic Virus Coat Proteins into Nanotubes with Uniform Length and Improved Physical Stability[J]. ACS APPLIED MATERIALS & INTERFACES,2016,8(21):13192-13196.
Service
Recommend this item
Sava as my favorate item
Show this item's statistics
Export Endnote File
Google Scholar
Similar articles in Google Scholar
[Zhou, K(周堃)]'s Articles
[Eiben, S]'s Articles
[Wang, QB(王强斌)]'s Articles
CSDL cross search
Similar articles in CSDL Cross Search
[Zhou, K(周堃)]‘s Articles
[Eiben, S]‘s Articles
[Wang, QB(王强斌)]‘s Articles
Related Copyright Policies
Null
Social Bookmarking
Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit
文件名: Zhou-2016-Coassembly of Tobacco Mosaic Virus C.pdf
格式: Adobe PDF
所有评论 (0)
暂无评论
 
评注功能仅针对注册用户开放,请您登录
您对该条目有什么异议,请填写以下表单,管理员会尽快联系您。
内 容:
Email:  *
单位:
验证码:   刷新
您在IR的使用过程中有什么好的想法或者建议可以反馈给我们。
标 题:
 *
内 容:
Email:  *
验证码:   刷新

Items in IR are protected by copyright, with all rights reserved, unless otherwise indicated.

 

 

Valid XHTML 1.0!