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题名: Facile synthesis of magnetic-plasmonic nanocomposites as T (1) MRI contrast enhancing and photothermal therapeutic agents
作者: Yang, ZZ(杨钟贞); Ding, XG(丁显光); Jiang, J(姜江)
通讯作者: Jiang, J(姜江)
刊名: NANO RESEARCH
发表日期: 2016
DOI: 10.1007/s12274-015-0958-9
卷: 9, 期:3
收录类别: SCI ; EI
文章类型: 期刊论文
部门归属: 纳米研究国际实验室
英文摘要: Nanocomposites combining magnetic and plasmonic components have received widespread attention in recent years due to their potential applications in biomedical research. Herein, we describe a facile method for growing small iron oxide nanoparticles on various plasmonic core materials with different shapes and surfaces by utilizing a polypyrrole interlayer. By focusing on Au nanorod@polypyrrole@iron oxide (Au NR@PPy@Fe (x) O) nanocomposites, we show that these systems exhibit a low r (2)/r (1) ratio of 4.8, making them efficient T (1) positive contrast-enhancing agents for magnetic resonance imaging (MRI). Moreover, we show that the nanocomposites are excellent photothermal agents in the second near infrared region, with high photothermal conversion efficiency, reaching up to 46%. In addition, the Au NR@PPy@Fe (x) O nanocomposites show very low cytotoxicity. In summary, the present results highlight the great potential of the synthetic method and the nanocomposites developed in this study for T (1) MRI and/or infrared thermal imaging-guided photothermal cancer therapeutic applications.
关键词[WOS]: IN-VIVO ; POLYPYRROLE NANOPARTICLES ; OXIDE NANOPARTICLES ; CANCER-THERAPY ; INORGANIC NANOPARTICLES ; SHELL NANOPARTICLES ; GOLD NANOPARTICLES ; RESONANCE ; CELLS ; GADOLINIUM
语种: 英语
JCR小类分区: 一区
WOS记录号: WOS:000371797000020
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinano.ac.cn/handle/332007/4585
Appears in Collections:纳米研究国际实验室_姜江团队_期刊论文

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Recommended Citation:
Yang, ZZ,Ding, XG,Jiang, J. Facile synthesis of magnetic-plasmonic nanocomposites as T (1) MRI contrast enhancing and photothermal therapeutic agents[J]. NANO RESEARCH,2016,9(3).
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