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题名: 3D printed printed PEGDA microstructures for gelatin scaffold integration and neuron differentiation
作者: Tu, XL; Wang, LN; Wei, J; Wang, B; Tang, YD; Shi, J; Zhang, ZJ(张智军); Chen, Y
通讯作者: Chen, Y
刊名: MICROELECTRONIC ENGINEERING
发表日期: 2016
DOI: 10.1016/j.mee.2016.03.007
卷: 158
收录类别: SCI
文章类型: 期刊论文
部门归属: 纳米生物医学与安全研究部
英文摘要: Three dimensional (3D) printing techniques can be used for scaffold fabrication but the most of them are limited by resolution and material choice. To bypass these limitations, we developed an approach by combining conventional 3D printing and freeze-drying techniques to produce lattice-type backbone and embedding microporous structures. Polyethylene glycol diacrylate (PEGDA), a biocompatible and photosensitive pre-polymer, was chosen for 3D printing of the backbone, while gelatin was used for the formation of microporous structures. The fabricated PEGDA/gelatin scaffolds were used for culture and differentiation of neural progenitor cells (NPCs), showing infiltration of the cells and outgrowth of differentiated neurites. This strategy of combined use of 3D printing and freeze-drying techniques might be useful for scaffold fabrication in terms of easy design and easy material processing. (C) 2016 Elsevier B.V. All rights reserved.
关键词[WOS]: HYDROGELS ; TISSUE ; BIOMATERIALS ; FABRICATION ; THERAPIES ; NETWORKS
语种: 英语
JCR小类分区: 四区
WOS记录号: WOS:000378962800009
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinano.ac.cn/handle/332007/4693
Appears in Collections:纳米生物医学与安全研究部_张智军团队_期刊论文

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Recommended Citation:
Tu, XL,Wang, LN,Wei, J,et al. 3D printed printed PEGDA microstructures for gelatin scaffold integration and neuron differentiation[J]. MICROELECTRONIC ENGINEERING,2016,158.
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