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题名: Mass production of shaped particles through vortex ring freezing
作者: An, D; Warning, A; Yancey, KG; Chang, CT; Kern, VR; Datta, AK; Steen, PH; Luo, D(罗丹); Ma, ML
通讯作者: Luo, D(罗丹) ; Ma, ML
刊名: Nature Communications
发表日期: 2016
DOI: 10.1038/ncomms12401
卷: 7
收录类别: SCI ; EI
文章类型: 期刊论文
部门归属: 纳米生物医学与安全研究部
英文摘要: A vortex ring is a torus-shaped fluidic vortex. During its formation, the fluid experiences a rich variety of intriguing geometrical intermediates from spherical to toroidal. Here we show that these constantly changing intermediates can be 'frozen' at controlled time points into particles with various unusual and unprecedented shapes. These novel vortex ring-derived particles, are mass-produced by employing a simple and inexpensive electrospraying technique, with their sizes well controlled from hundreds of microns to millimetres. Guided further by theoretical analyses and a laminar multiphase fluid flow simulation, we show that this freezing approach is applicable to a broad range of materials from organic polysaccharides to inorganic nanoparticles. We demonstrate the unique advantages of these vortex ring-derived particles in several applications including cell encapsulation, three-dimensional cell culture, and cell-free protein production. Moreover, compartmentalization and ordered-structures composed of these novel particles are all achieved, creating opportunities to engineer more sophisticated hierarchical materials.
关键词[WOS]: WATER DROP ; DYNAMICS ; HYDROGEL ; FLOW ; ENCAPSULATION ; MICROSPHERES ; GENERATION ; EVOLUTION ; CLAY
语种: 英语
JCR小类分区: 一区
WOS记录号: WOS:000380863000001
Citation statistics:
内容类型: 期刊论文
URI标识: http://ir.sinano.ac.cn/handle/332007/4929
Appears in Collections:纳米生物医学与安全研究部_离职团队_期刊论文

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Recommended Citation:
An, D,Warning, A,Yancey, KG,et al. Mass production of shaped particles through vortex ring freezing[J]. Nature Communications,2016,7.
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文件名: Mass production of shaped particles through vortex ring freezing.pdf
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